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Arbutin is commercially used as a skin-whitening agent in cosmetic industry. It works by competitive inhibition of tyrosinase, a key enzyme in the synthesis of melanin.
Depending on the spatial structure of the glycosidic linkage between glucose and hydroquinone, Arbutin forms two epimers: α-Arbutin and β-Arbutin.
Botanical Source Of Beta-Arbutin: bearberry
Beta Arbutin is commonly referred to as just Arbutin. It is can be naturally extracted from plants such as bearberry and synthesized by chemical method. Beta Arbutin is currently one of the most widely used hypopigmenting agents in cosmetics, while plant-derived drugs containing Beta-Arbutin were initially used for the treatment of urinary tract infections, cystitis, kidney stones, and as diuretics in the medical field.
Alpha Arbutin is enzymatically synthesized from hydroquinone and saccharides through transglycosylation reaction. Various carbohydrate-active enzymes such as α-amylase, α-glucosidase, transglucosidase, sucrose phosphorylase, and dextransucrase have been employed to synthesize Alpha Arbutin. It is one of the most advanced skin lightening ingredients on the market.
Arbutin is used as a skin whitening agent in cosmetic formulations. Arbutin soap, cream, serum and lotion are among the major lightening products in the market.
Arbutin’s advantage over traditional skin-whitening products:
Arbutin can inhibit melanogenesis without causing melanocyte toxicity, unlike traditional depigmenting agents such as hydroquinone, corticosteroids.
Arbutin cosmetics examples
Arbutin Cosmetic Formula Reference
Anti-freckle whitening essence
β-Arbutin breaks down easily in acidic conditions, so the pH value of cosmetics containing β-Arbutin should be about 7.0
Please dissolve β-Arbutin in 50℃ hot water before adding it to skin whitening products. (β-Arbutin is soluble in hot water, methanol or alcohol. β-Arbutin is partially soluble in cold water. β-Arbutin is insoluble in aether, chloroform or benzene.)
Antioxidants should be added to cosmetics containing β-Arbutin.
Package and Storage
Package: Aluminium foil bag with plastic bag for 1-10kg. Paper drum with two plastic bags for 25kg.
Storage: Please tightly sealed Arbutin in containers. Store it in a cool dry place and away from sunlight and oxidizing agents.
A customer from Nigeria:
Your Arbutin is good. Thanks to you and your team. I will also buy the Tetrahydocucurmin, and small of glabridin.
A customer from Rwanda:
Very good. I will keep you posted and I have noticed brightening effect with the very first use!!!
Why there is low priced Alpha Arbutin on the market?
Melanins are irregular polymeric structures derived from the amino acid tyrosine, and tyrosinase is known to be one of the key enzymes in mammalian melanin synthesis.
Tyrosinase is a copper-containing enzyme that catalyzes the rate-limiting step of melanin synthesis, which is oxidation of the aromatic amino acid tyrosine to DOPA and subsequently to DOPA-quinone. DOPA-quinone is then converted by multi-step reactions to melanin. As a result, tyrosinase is responsible for the formation of pigments such as melanins and other polyphenolic compounds from tyrosine by oxidation reactions.
Suitable for under 50kg
Fast: 7-15 days
Door to door service
easy to pick up the goods
Suitable for more than 50kg
Fast: 7-15 days
Port to port
professional broker needed
Suitable for more than 500kg
Slow: 7-45 days
Port to port
professional broker needed
How To Buy Arbutin
Paypal(Suitable for under 500USD)
Western Union(Suitable for under 5000USD)
Bank Transfer(Suitable for all amount)
15% charges Arrive time: immediately Easy to
Reasonable bank charges Arrive time: immediately Easy
Reasonable bank charges Arrive time:2-3 work days Easy
Arbutin Manufacturers And Laboratory Shows
Arbutin, Alpha Arbutin, Beta Arbutin factory
With an investment of 80 million RMB, the construction of the factory started from 2012 and was finished at 2014. There are three production lines that meet the GMP standard in our factory which can process 6,000 ton raw materials each year with production of 900 ton plant extract. Our factory has been issued with the GMP certificate by China Food and Drug Administration in the year 2014.
Arbutin, Alpha Arbutin, Beta Arbutin manufacturer GMP Production Line
Plant extract testing laboratory
Due to the complexity of plant extract and the deficiency industrial standards, one of our founders established a professional testing lab with an investment of 15 million RMB in 2014. The laboratory is equipped with five High performance liquid chromatography, one Gas Chromatograph, one Atomic Absorption Spectrometer, one Liquid mass spectrometry, one TLC scanner, one Automatic polarimeter, one Infrared Spectrometer, one Automatic melting point apparatus, one Mold incubator, one UV-visible spectrophotometer, one Portable Pressure Steam Sterilizer, one Single clean bench, one Explorer quasi-microbalance, one Electronic balance, and one Experimental resistance furnace.
Our Mission And Philosophy
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To ensure that the production process is under our control, we have built factory of our own, what’s more, we have bought the most shares of several high-quality manufacturers. From raw material selection, to every specific production procedure, to the storage of every kind of product, every detail is under the inspection of our specialists with at least ten years’ experience.