5 HTP

$55.00/KG
Specification:
Test by: HPLC
Quantity:
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5 HTP Introduction

5-HTP (5-Hydroxytryptophan) is an amino acid. Amino acids are substances that build proteins in your body. It is also produced commercially from the seeds of an African plant (Griffonia simplicifolia). 5-HTP is related to serotonin, a brain chemical that affects mood, sleep, and pain. It is of the Pharmaceutical grade.

Active ingredient: 5-HTP CAS Number: 56-69-9 (114-03-4)
Molecular formula: C11H12N2O3 Molecular weight: 220.23
Molecular formula:

 

Where are 5 HTP extracted from?

Most 5-HTP also known as oxitriptan (INN) is extracted from the seeds of a woody climbing shrub native to West Africa, called the Griffonia simplicifolia plant. It is the largest source of the compound 5-HTP. Its seeds contain up to 10-15% 5-HTP, by weight.

5 HTP Specification(COA)

ANALYSIS

SPECIFICATION

RESULTS

Remark

Assay

 L-5-HTP≥28%

28.67% 

HPLC

Appearance 

Fine Yellowish-Brown powder

Fine Yellowish-Brown powder

Visual

Identification

Identification

 

Retention time of L-5-HTP Peak matches with the L-5-HTP R.S

Retention time of L-5-HTP Peak matches with the L-5-HTP R.S

HPLC

Physical  Characteristics

Particle size

100% pass 80 mesh

100% pass 80 mesh

80 Mesh Screen

Loss of drying

≤5.0%

3.10%

2~5g/105℃/5hrs

(CP2010  Appendix IX G 52 )

Residual on Ignition

≤5.0%

0.70%

2g/525℃/3hrs

(CP2010  Appendix IX J 53)

Impurity

Heavy Metal

(As Pb)

≤20ppm

Conforms

Thioacetamide Colorimetric Method (CP2010 Appendix IXE 50 1st method)

As (As  As2O3)

≤3ppm

Conforms

AAS

Lead(Pb)

≤3ppm

Conforms

AAS

Cadmium(Cd)

≤1ppm

Conforms

AAS

Mercury(Hg)

≤0.1ppm

Conforms

AAS

Aflatoxins

≤10ppb

Conforms

HPLC

Residual Solvents

 

 

 

Ethanol

≤ 5000ppm

Conforms

GC

Microbiological Characteristics

Total Plate Count

< 10000 cfu/g     

Conforms

Plate count method

(CP2010 Appendix XIII C 79)

Yeast and Mold

< 100 cfu/g

Conforms

Plate count method

(CP2010 Appendix XIII C 79)

Coliforms

< 10 cfu/g

Conforms

Plate count method

(CP2010 Appendix XIII C 79)

Escherichia Coli

Negative

Negative

Plate count method

(CP2010 Appendix XIII C 79)

Salmonella enteritica

Negative

Negative

Plate count method

(CP2010 Appendix XIII C 79)

Staphylococcus aureus

Negative

Negative

Plate count method

(CP2010 Appendix XIII C 79)

 

ANALYSIS

SPECIFICATION

RESULTS

Remark

 

Assay

 5-HTP≥98%

98.7% 

HPLC

Peak X

Negative

No Detected

HPLC

Appearance

White fine powder

Conform

Visual

Smell

Characteristic odor

Conform

Scent

Loss on Drying

≤ 5.0%

1.50%

5g/105℃/2hrs

Ash content

≤ 1.0%

0.35%

5g/525℃/2hrs

Solvent residue

≤500mg/kg

33mg/kg

GC

Sieve

98% pass 80 mesh

Conform

80 mesh screen

Total Heavy Metals

≤ 10ppm

Conform

CP2010

Lead (Pb)

≤ 1ppm

0.35ppm

CP2010(AAS)

Arsenic (As)

≤ 1ppm

0.11ppm

CP2010(AAS)

Total Plate Count

1000CFU/Gr. Max

260CFU/Gr.

CP2010

Yeast& Mold

100CFU/Gr. Max.

10CFU/Gr.

2CP2010

E.Coli

Negative

Conform

CP2010

Salmonella

Negative

Conform

CP2010

 

ANALYSIS

SPECIFICATION

RESULTS

Remark

 

Assay

 L-5-HTP≥99%

99.05% 

HPLC

Appearance 

Off-white powder

Off-white powder

Visual

Identification

Identification

 

Retention time of L-5-HTP Peak matches with the L-5-HTP R.S

Retention time of L-5-HTP Peak matches with the L-5-HTP R.S

HPLC

Specific Rotation [a]D20

-32.5±2.0o(C=1, H2O)

-32.5

C=1, H2O

Physical  Characteristics

Particle size

NLT 95% pass 80 mesh

99% pass 80 mesh

80 Mesh Screen

Loss of drying

≤2.0%

0.35%

2~5g/105℃/5hrs

Residual on Ignition

≤1.0%

0.2%

2g/525℃/3hrs

Impurity

Heavy Metal

(As Pb)

≤20ppm

Complies

Thioacetamide Colorimetric Method

As (As  As2O3)

≤2ppm

Complies

AAS

Lead(Pb)

≤2ppm

Complies

AAS

Cadmium(Cd)

≤1ppm

Complies

AAS

Mercury(Hg)

≤1ppm

Complies

AAS

Aflatoxins

≤10ppb

Complies

HPLC 

Residual Solvents

 

 

 

Ethanol

USP<467>

Complies

USP35

Pesticides Solvents

Pesticides

USP<561>

Complies

USP35

Microbiological Characteristics

Total Plate Count

< 1000 cfu/g

Complies

GB 4789.2-2010

Yeast and Mold

< 100 cfu/g

Complies

GB 4789.15-2010

Coliforms

Negative

Negative

GB 4789.3-2010

Escherichia Coli

Negative

Negative

GB 4789.6-2010

Salmonella enteritica

Negative

Negative

GB 4789.4-2010

Staphylococcus aureus

Negative

Negative

GB 4789.2-2010

 

Extraction Process


 

5 HTP Benefit and Dosage

1. Depression

Some trials using 5-HTP with people suffering from depression indicate that 5-HTP may work as well as certain antidepressant drugs to treat people with mild-to-moderate depression. Depression has been linked to serotonin deficiency in the brain. Supplementing with 5-HTP may increase the levels of serotonin and reduce symptoms.

Recommended Dosage —— Several trials have found that doses of 100-300 mg daily for 2-4 weeks can improve symptoms of depression.

2. Fibromyalgia

Research suggests that 5-HTP can improve symptoms of fibromyalgia, including pain severity, morning stiffness, and sleeplessness. People with fibromyalgia often have low serotonin levels in their blood. Supplementation with 5-HTP may increase serotonin synthesis in these cases.

Recommended Dosage —— Several trials have reported that 5-HTP supplementation (100 mg three times per day) relieves some symptoms of fibromyalgia.

3. Insomnia

In one study, people who took 5-HTP went to sleep quicker and slept more deeply than those who took a placebo, presumably because it is converted to the chemical messenger, serotonin.

Recommended Dosage —— Researchers recommend 200 mg two hours before bedtime and 400 mg at bedtime for adult for 6 to 12 weeks, while for children with sleep terrors the recommended dosage is 3 mg/kg/day given at bedtime for 20 days.

*The Content here is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician with any questions you may have regarding a medical condition.

Product packaging

0-1kg

1-10kg

10-25kg

Shipping

By Express By Air By Sea
Suitable for under 50kg
Fast: 7-15 days
High cost
Door to door service
easy to pick up the goods
Suitable for more than 50kg
Fast: 7-15 days
High cost
Port to port
professional broker needed
Suitable for more than 500kg
Slow: 7-45 days
Low cost
Port to port
professional broker needed

How To Buy 5 HTP

Paypal(Suitable for under 500USD) Western Union(Suitable for under 5000USD) Bank Transfer(Suitable for all amount)
15% charges
Arrive time: immediately
Easy to handle
Reasonable bank charges
Arrive time: immediately
Easy to handle
Reasonable bank charges
Arrive time:2-3 work days
Easy to handle

5 HTP Manufacturers And Laboratory Shows

5 HTP factory

With an investment of 80 million RMB, the construction of the factory started from 2012 and was finished at 2014. There are three production lines that meet the GMP standard in our factory which can process 6,000 ton raw materials each year with production of 900 ton plant extract. Our factory has been issued with the GMP certificate by China Food and Drug Administration in the year 2014.

5 HTP manufacturer GMP Production Line

Plant extract testing laboratory

Due to the complexity of plant extract and the deficiency industrial standards, one of our founders established a professional testing lab with an investment of 15 million RMB in 2014. The laboratory is equipped with five High performance liquid chromatography, one Gas Chromatograph, one Atomic Absorption Spectrometer, one Liquid mass spectrometry, one TLC scanner, one Automatic polarimeter, one Infrared Spectrometer, one Automatic melting point apparatus, one Mold incubator, one UV-visible spectrophotometer, one Portable Pressure Steam Sterilizer, one Single clean bench, one Explorer quasi-microbalance, one Electronic balance, and one Experimental resistance furnace.

Our Mission And Philosophy

Where to buy 5 HTP? Where to find good 5 HTP Manufacturers and 5 HTP suppliers? Where can i Looking for 5 HTP purchase? Where can i purchase 5 HTP price and where to get 5 HTP for sale? Is that the very question that lingers in your mind every time you do purchasing? Well, that should not be your headache any longer since we are committed to help you get rid of it completely. We can provide you with the safest and most effective 5 HTP. To ensure the quality of any products that you buy on your platform, we have signed an investment and cooperation agreement with Natural Medicine Public Technical Service Platform, the largest and most professional third-party testing agency in China. Any extract you buy will have to pass the test of our strategic partner before delivery.
To ensure that the production process is under our control, we have built factory of our own, what’s more, we have bought the most shares of several high-quality manufacturers. From raw material selection, to every specific production procedure, to the storage of every kind of product, every detail is under the inspection of our specialists with at least ten years’ experience.